We tried these things out on our road race bikes (GXXR's 600, 750 & 1000) and found they do indeed decrease power on the top end. I also tried one on my busa and couldn't tell any noticeable difference in power anywhere.
Little quick story. I had a track day customer who had a GSXR1000 K7 just like mine who ask me if I had a TRE on my bike. Nope! He continued to tell me how much more power and how blazing fast it made his bike. Unbelievable I belive was the term he used. After I passed him with relative ease on the front straight I never heard another peep about the TRE thing. Only he was using "Unbelieveable" in a different context.