I've been riding mine daily for about 5 months. My other (running) vehicle is a 454 crew cab dually, so I get 3-4X the fuel mileage riding the bike.
I ride in the rain unless it's really storming hard, or if I need to take my Great Dane somewhere...etc.
The biggest hassle is putting on and off the gear. Sometimes that takes as long as actually getting to the "corner store"...actually making the truck quicker to get there and back to my couch.
Get yourself a selection of tank bags so you can do grocery shopping and such (one bag's worth anyway).
A medium sized (12L?) magnetic for around town, and a larger bag (i.e....XL bag) for times when you need to carry a bit more. I would suggest the larger bag use straps, and you can leave those on.
You'd be surprised how much you use tank bags when riding daily even for small stuff. It keeps me from having to fill and empty my pockets all the time. Just toss in wallet, phone, keys...all in one place. If I decide I need milk, or a trip through the drive through... you quickly learn to pack it (don't order the soda).
If it rains in your part of the world, put a hand towel in the tank bag...comes in handy, and possibly a high-vis rain coat that you can put over your MC jacket.
My particular Busa is set up for an older man...
It has:
Helibars (slightly easier on the wrists)
Knight lowered foot pegs (knees and back)
Those don't really change the look of the bike much...even when riding (see Avatar photo), but they do make it a little more comfortable for sitting at lights or in traffic...etc.
All and all I've really enjoyed the Busa as a daily driver. I don't think I would want to be without something that had 4 wheels completely though. A low cost (insurance too) vehicle with heat/air/roof is one of the best Busa acc's I can think of.
Regards
Sean