When I dyno'd my 750 gixxer it actually made the pipes turn yellow. Stainless Yosh pipes. Never did get them polished up again. Your tire will wear for sure.
Also watch your wear....Dyno results and setups are affected by the wear on the tire. A bald or balding tire will give higher(slightly better) dyno results. Kinda like cheating. Use rubber that you would like to drive on.