In my humble 45 years of riding bikes, I have found no other big bike as gentle and forgiving as the busa. It's a gentle beast that will take you any place you want to go in style with ease. Does it have power, yes! But,,,,,,,, you must crank the throttle open to unleash the demon. Just think of it in the same way as when your daddy taught you to drive and said to push on the gas pedal as if you had an egg under your foot. Same with the busa. Give it gas as if you were trying to pick an egg up with a thread, very gently. You'll find the busa very easy to manage.
I would much rather see you on a busa as a first bike than any of the liter bikes. The Gixxer, R1, ZX10 for example can all be classified as "Evil"! Any one of those are much more likely to bite you during the learning curve than the busa. I taught Scootergirl to ride a busa with very little experience. She had no trouble whatsoever and dearly loves her busa. I taught her to ride on a 800 Intrucer which weighed in at 535 pounds, fifty pounds heavier than the busa. So if a 130 pound woman can manage a bike that heavy as a learner, doesn't say much for the wieght lifter who thinks you have to squat a ton to straddle a busa
Riding bike is a lot more about balance, hand eye cordination, etc, than it is about strength.
My advice is, if you want a busa, by all means buy one. If you drop it, which you probably will and most folks don't crash them learning to ride, they drop them in a parking lot trying to go slow. Just put a few bucks away to buy some new plastic when you scratch up the side panels.
Also, find yourself an experienced sport bike rider to help you through the learning curve. It will save you lots of headaches. Go take a motorcycle safety course before your purchase no matter what you buy. The course will give you a little riding time and pointers to get you started. For the first month, always ride with a friend. In case you drop it, it's a heavy beast to upright by yourself, that's where the guy with the strong legs would come in handy.
For those who tell you to start out on a 600? That's not bad advice but IMO a 600 goes 160 MPH and I'm not sure slamming into a tree or bridge abuttment at 160 on a 600 will have any different results than doing the same on a busa at 180 MPH? Use good judgment and common sense and you'll live to be old and gray like me, get stupid and most likely you'll become a statistic early on, no matter what bike you decide to purchase!
Good Luck on your biking adventure and welcome to this board. Lots of good guys here!