This Kollywood remake of Frankenstein finds scientist Vasi (Rajnikanth) using himself as the model for his creation, an emotionless robot named Chitti. When a scientific board rejects his android, Vasi reprograms Chitti with disastrous results. While processing the sensory input of his new world, Chitti falls in love with Vasi's fiancée, Sana (Aishwarya Rai), and is targeted by Vasi's mentor, who seeks to harness his powers.