Nitrous is the cheapest way to make HP of all of them. Turbo and Supercharger are next. But all of these have problems. Nitrous is limited by how much nitrous you carry and can grenade an engine instantly if it malfunctions. Turbos and SCs are limited by tetonation due to heat from compression and fuel/octane supply. They can blow a hole in a piston like it is butter if it leans out and detonates at high RPM. I used the Whipple supercharger on my boat to go from 330HP to 520HP running 92 octane pump gas at 5 PSI boost. Very reliable with the intercooler and no change to the engine at all. But nothing come close to normally aspirated for reliability. It does cost more to make as much HP using normal aspiration as nitrous or a blower. For the street / long trips, I would stick to normally aspirated. If you are at all concerned about gas mileage, the nitrous is the way to go since it only needs more gas when it is activated. Otherwise it runs the same as a stock engine. Big displacement engines make more HP all the time and therefore need more gas all the time. Turbos are inbetween since at low RPM (cruising) they don't make much boost and only need slightly more gas than stock. Then as the RPM and boost rise the fuel consumption is greater.
The big bore kits Muzzy and others sell are what I will try when I use up the stock engine. Stroking the engine is great for torque but can lower your max RPM and can limit your Max HP increase. You need stronger rods and special short skirt pistons that cost more $. It creates other strength concerns in the engine such as crank flexure and case flexure that can short the engine's life. Sometimes the cases have to be milled out to gain enough clearance for the crank to swing. That weakens the case when you are going to put more forces through it. Not a great idea.